The advent of new weight loss drugs has a huge impact on everyone in South Park. When Cartman is denied access to the life-changing medicine, the kids jump into action.

Cartman locks horns with his mom in a battle of wills while an epic conflict unfolds that threatens South Park’s very existence.

Viewers will get a look at Parker and Stone’s thought process as they approach a new episode and the 24/7 grind they subject themselves to each time the show is…