Spotted by a producer in Mediacorp in 2004, Jesseca Liu was offered the meaty role of He Yi Xuan in the sports-themed drama, βThe Championβ. From then, she began her career as a full-time actress in Singapore. Her portrayal of a Vietnamese bride in the 100-episode drama serial βPortrait of Homeβ bagged her the Most Popular Newcomer Award and earned her a Best Supporting Actress nomination at Star Awards 2005. She scored her first leading role in βRhapsody In Blueβ in 2006 which led to more lead roles for the popular star. She played the female lead in many Mediacorp highly-rated serials including βSecrets For Saleβ, βThe Oathβ, βMarry Meβ, βBlessingsβοΌβ Mind MattersβοΌβ Babies On Boardβ and βHeroβ. In 2014, she wrote her first web drama script, βWho Killed The Leadβ where she played the female lead and the script was awarded for Best Digital Fiction & Non-Fiction Series at the Asian Television Awards. She also played the role of a mother for the first time and paired with Taiwan actor-host Jacko Chiang in a local movie, βBring Back The Deadβ. Most recently, she received the "Outstanding Leading Actress in Comedy" Award at the 2019 Asia Rainbow TV Awards for her role in